KhtU

• Description: K+/H+ antiporter for K+ efflux
  
  

Gene name	yhaU
Synonyms
Essential	no
Product	K+/H+ antiporter for K+ efflux
Function	potassium ion efflux
Interactions involving this protein in SubtInteract: YhaU
MW, pI	43 kDa, 9.293
Gene length, protein length	1224 bp, 408 aa
Immediate neighbours	hemZ, yhaT
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), membrane proteins

The gene

Basic information

• Locus tag: BSU09850

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: View classification (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YhaT-YhaU PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O07536

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Makoto Fujisawa, Masahiro Ito, Terry A Krulwich
Three two-component transporters with channel-like properties have monovalent cation/proton antiport activity.
Proc Natl Acad Sci U S A: 2007, 104(33);13289-94
[PubMed:17679694] [WorldCat.org] [DOI] (P p)

Makoto Fujisawa, Yuko Wada, Masahiro Ito
Modulation of the K+ efflux activity of Bacillus subtilis YhaU by YhaT and the C-terminal region of YhaS.
FEMS Microbiol Lett: 2004, 231(2);211-7
[PubMed:14987767] [WorldCat.org] [DOI] (P p)