Difference between revisions of "RnpB"
| Line 52: | Line 52: | ||
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG00045] | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG00045] | ||
| − | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2A64 2A64] (from Geobacillus stearothermophilus) | + | * '''Structure:''' |
| − | + | ** [http://www.rcsb.org/pdb/explore.do?structureId=2A64 2A64] (from ''Geobacillus stearothermophilus'') | |
| − | + | ** [http://www.rcsb.org/pdb/explore.do?structureId=1NBS 1NBS] (specificity domain) | |
| + | ** [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3OKB 3OKB] (complex of RnpA with the RNA RnpB and tRNA, from ''Thermotoga maritima'') {{PubMed|21076397}} | ||
=The RNA= | =The RNA= | ||
| Line 106: | Line 107: | ||
==Original Publications== | ==Original Publications== | ||
<pubmed>16470227,17355991,11812129,10390342,11454206, 19549719,11454206, 19717440 ,20133747 19932118 20188108 20434461 17299131 14510496 12951523 12836338 11577704 20557101 </pubmed> | <pubmed>16470227,17355991,11812129,10390342,11454206, 19549719,11454206, 19717440 ,20133747 19932118 20188108 20434461 17299131 14510496 12951523 12836338 11577704 20557101 </pubmed> | ||
| − | + | '''Additional publications:''' {{PubMed|21076397}} | |
[[Category:small RNA]] | [[Category:small RNA]] | ||
Revision as of 15:13, 15 December 2010
- Description: RNA component of RNase P
| Gene name | rnpB |
| Synonyms | rnaP |
| Essential | no |
| Product | RNA component of ribonuclease P (RNase P) (catalytic subunit, ribozyme) |
| Function | cleavage of precursor sequences from the 5' ends of pre-tRNAs |
| Gene length | 401 bp |
| Immediate neighbours | ypsC, ypsB |
| Gene sequence (+200bp) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
- Structure:
The RNA
- Biological activity: 5' end maturation of precursor tRNAs
- RNA family:
- cofactor: divalent cations (Ca(II) or Mg (II)) for the stabilization of the complex with pre-tRNA PubMed
- interaction: RnpA-RnpB
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/RNA
- Carol Fierke, University of Michigan, Ann Arbor, USA homepage
- Roland Hartmann, Marburg University, Germany homepage
Your additional remarks
References
Reviews
Roland K Hartmann, Markus Gössringer, Bettina Späth, Susan Fischer, Anita Marchfelder
The making of tRNAs and more - RNase P and tRNase Z.
Prog Mol Biol Transl Sci: 2009, 85;319-68
[PubMed:19215776]
[WorldCat.org]
[DOI]
(P p)
J Kristin Smith, John Hsieh, Carol A Fierke
Importance of RNA-protein interactions in bacterial ribonuclease P structure and catalysis.
Biopolymers: 2007, 87(5-6);329-38
[PubMed:17868095]
[WorldCat.org]
[DOI]
(P p)
Alexei V Kazantsev, Norman R Pace
Bacterial RNase P: a new view of an ancient enzyme.
Nat Rev Microbiol: 2006, 4(10);729-40
[PubMed:16980936]
[WorldCat.org]
[DOI]
(I p)
Donald Evans, Steven M Marquez, Norman R Pace
RNase P: interface of the RNA and protein worlds.
Trends Biochem Sci: 2006, 31(6);333-41
[PubMed:16679018]
[WorldCat.org]
[DOI]
(P p)
Alfredo Torres-Larios, Kerren K Swinger, Tao Pan, Alfonso Mondragón
Structure of ribonuclease P--a universal ribozyme.
Curr Opin Struct Biol: 2006, 16(3);327-35
[PubMed:16650980]
[WorldCat.org]
[DOI]
(P p)
John Hsieh, Andy J Andrews, Carol A Fierke
Roles of protein subunits in RNA-protein complexes: lessons from ribonuclease P.
Biopolymers: 2004, 73(1);79-89
[PubMed:14691942]
[WorldCat.org]
[DOI]
(P p)
Enno Hartmann, Roland K Hartmann
The enigma of ribonuclease P evolution.
Trends Genet: 2003, 19(10);561-9
[PubMed:14550630]
[WorldCat.org]
[DOI]
(P p)
Original Publications
Additional publications: PubMed
