Difference between revisions of "Icd"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[citZ]]-[[icd]]-[[mdh]]'' |
| − | * '''Sigma factor:''' | + | * '''Sigma factor:''' [[SigA]] |
| − | * '''Regulation:''' | + | * '''Regulation:''' catabolite repression ([[CcpA]]), repression by glucose + glutamate ([[CcpC]]) |
| − | * '''Regulatory mechanism:''' | + | * '''Regulatory mechanism:''' [[CcpA]]: transcription repression, [[CcpC]]: transcription repression |
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 15:53, 9 February 2009
- Description: write here
| Gene name | icd |
| Synonyms | citC |
| Essential | |
| Product | isocitrate dehydrogenase (EC 1.1.1.42) |
| Function | |
| MW, pI | 46 kDa, 4.833 |
| Gene length, protein length | 1269 bp, 423 aa |
| Immediate neighbours | |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry:
- E.C. number:
Additional information
Expression and regulation
- Sigma factor: SigA
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Matsuno K, Blais T, Serio AW, Conway T, Henkin TM, Sonenshein AL (1999) Metabolic imbalance and sporulation in an isocitrate dehydrogenase mutant of Bacillus subtilis. J Bacteriol 181:3382-3391. PubMed
- Singh SK, Miller SP, Dean A, Banaszak LJ, LaPorte DC (2002) Bacillus subtilis isocitrate dehydrogenase. A substrate analogue for Escherichia coli isocitrate dehydrogenase kinase/ phosphatase. J Biol Chem 277: 7567-7573. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
