Difference between revisions of "RplA"

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= [[Categories]] containing this gene/protein =
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{{SubtiWiki category|[[translation]]}},
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{{SubtiWiki category|[[essential genes]]}},
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{{SubtiWiki category|[[universally conserved proteins]]}}
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= This gene is a member of the following [[regulons]] =
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{{SubtiWiki regulon|[[stringent response]]}}
  
 
=The gene=
 
=The gene=
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= Categories containing this gene/protein =
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{{SubtiWiki category|[[translation]]}},
 
{{SubtiWiki category|[[essential genes]]}},
 
{{SubtiWiki category|[[universally conserved proteins]]}}
 
 
=The protein=
 
=The protein=
  

Revision as of 15:23, 8 December 2010

Gene name rplA
Synonyms
Essential yes PubMed
Product ribosomal protein L1 (BL1)
Function translation
MW, pI 24 kDa, 9.732
Gene length, protein length 696 bp, 232 aa
Immediate neighbours rplK, rplJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RplA context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

translation, essential genes, universally conserved proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU01030

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ribosomal protein L1P family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Stülke lab
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Matthew A Lauber, William E Running, James P Reilly
B. subtilis ribosomal proteins: structural homology and post-translational modifications.
J Proteome Res: 2009, 8(9);4193-206
[PubMed:19653700] [WorldCat.org] [DOI] (P p)

Catherine Wicker-Planquart, Anne-Emmanuelle Foucher, Mathilde Louwagie, Robert A Britton, Jean-Michel Jault
Interactions of an essential Bacillus subtilis GTPase, YsxC, with ribosomes.
J Bacteriol: 2008, 190(2);681-90
[PubMed:17981968] [WorldCat.org] [DOI] (I p)

J Mascarenhas, M H Weber, P L Graumann
Specific polar localization of ribosomes in Bacillus subtilis depends on active transcription.
EMBO Rep: 2001, 2(8);685-9
[PubMed:11463749] [WorldCat.org] [DOI] (P p)