Difference between revisions of "McpB"

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* '''Description:''' methyl-accepting chemotaxis protein <br/><br/>
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* '''Description:''' methyl-accepting chemotaxis protein, receptor for asparagine <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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* '''Interactions:''' [[CheA]]-[[McpB]] {{PubMed|19864420}}, [[McpB]]-[[CheC]] {{PubMed|11722727}}
 
* '''Interactions:''' [[CheA]]-[[McpB]] {{PubMed|19864420}}, [[McpB]]-[[CheC]] {{PubMed|11722727}}
  
* '''Localization:''' cell membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
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* '''Localization:'''  
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** cell membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
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** localized at the cell poles, but in the presence of high asparagine concentration there is a reversible re-localization to the sides of the cell (lateral clusters) {{PubMed|21098025}}
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
  
<pubmed>11722727,10825179,8251536,12909020,10196193,15544802,6137212,9194713,2505839,8188684,2105313,12123464,14731274,20864474 ,18763711, 19864420 </pubmed>
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<pubmed>11722727,10825179,8251536,12909020,10196193,15544802,6137212,9194713,2505839,8188684,2105313,12123464,14731274,20864474 ,18763711, 19864420 21098025 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 18:19, 1 December 2010

  • Description: methyl-accepting chemotaxis protein, receptor for asparagine

Gene name mcpB
Synonyms
Essential no
Product methyl-accepting chemotaxis protein
Function control of chemotaxis
MW, pI 71 kDa, 5.13
Gene length, protein length 1986 bp, 662 aa
Immediate neighbours tlpA, tgl
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
McpB context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU31260

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

motility and chemotaxis, membrane proteins

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information: K(D) for asparagine: 14 myM PubMed
  • Domains:
  • Modification: methylated at residues Gln371, Glu630, and Glu637 PubMed
  • Cofactor(s):
  • Effectors of protein activity: asparagine (binds to the part of McpB that is exposed to the exterior) PubMed
  • Localization:
    • cell membrane PubMed
    • localized at the cell poles, but in the presence of high asparagine concentration there is a reversible re-localization to the sides of the cell (lateral clusters) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References