Difference between revisions of "GltR"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[transcription factors and their control]]}} | ||
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| + | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[GltR regulon]]}} | ||
=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 21:44, 8 December 2010
- Description: transcriptional regulator (LysR family)
| Gene name | gltR |
| Synonyms | yrdL |
| Essential | no |
| Product | transcriptional regulator (LysR family) |
| Function | unknown |
| MW, pI | 32 kDa, 6.653 |
| Gene length, protein length | 888 bp, 296 aa |
| Immediate neighbours | yrdN, yrdK |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
transcription factors and their control
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU26670
Phenotypes of a mutant
The function of this protein is unknown. However, certain mutant forms are able to activate expression of the gltA-gltB operon (and thus to replace the cognate activator protein GltC)
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: LysR family of transcription factors
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P94501
- KEGG entry: [3]
- E.C. number:
Additional information
The function of this protein is unknown. However, certain mutant forms are able to activate expression of the gltA-gltB operon (and thus to replace the cognate activator protein GltC)
Expression and regulation
- Operon: gltR (according to DBTBS)
- Regulation:
- Additional information:
Biological materials
- Mutant: GP345 (erm), available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Linc Sonenshein, Tufts University, Boston, MA, USA Homepage
Your additional remarks
References
B R Belitsky, A L Sonenshein
Altered transcription activation specificity of a mutant form of Bacillus subtilis GltR, a LysR family member.
J Bacteriol: 1997, 179(4);1035-43
[PubMed:9023181]
[WorldCat.org]
[DOI]
(P p)
