CapC

• Description: capsular polyglutamate biosynthesis
  
  

Gene name	capC
Synonyms	ywtA, pgsC
Essential	no
Product	unknown
Function	capsule synthesis
MW, pI	16 kDa, 9.672
Gene length, protein length	447 bp, 149 aa
Immediate neighbours	capA, capB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

capsule biosynthesis and degradation

This gene is a member of the following regulons

DegU regulon

The gene

Basic information

• Locus tag: BSU35890

Phenotypes of a mutant

no synthesis of the poly-gamma-glutamate capsule PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P96737

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: capB-capC-capA-capE PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism: activated by DegU-P PubMed

• Additional information: The operon is not expressed in the lab strain 168 due to lack of expression of DegQ resulting in inactivity of DegS and DegU

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Massimiliano Marvasi, Pieter T Visscher, Lilliam Casillas Martinez
Exopolymeric substances (EPS) from Bacillus subtilis: polymers and genes encoding their synthesis.
FEMS Microbiol Lett: 2010, 313(1);1-9
[PubMed:20735481] [WorldCat.org] [DOI] (I p)