Difference between revisions of "SknR"

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m (moved YqaE to SknR: 20889742)
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* '''Description:''' similar to transcriptional regulator (phage-related) (Xre family) <br/><br/>
+
* '''Description:''' transcription repressor of the ''[[yqaF]]-[[yqdA]]-[[yqaG]]-[[yqaH]]-[[yqaI]]-[[yqaJ]]-[[yqaK]]-[[yqaL]]-[[yqaM]]-[[yqaN]]'' operon of the skin element (Xre family) <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* essential in the wild type background (due to overexpression of the toxic proteins [[YqaH]] and [[YqaM]]) {{PubMed|20889742}}
 +
* no phenotype if deleted with the complete skin element {{PubMed|20889742}}
  
 
=== Database entries ===
 
=== Database entries ===
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' binds the yqaF promoter region to repress transcription of the ''[[yqaF]]-[[yqdA]]-[[yqaG]]-[[yqaH]]-[[yqaI]]-[[yqaJ]]-[[yqaK]]-[[yqaL]]-[[yqaM]]-[[yqaN]]'' operon {{PubMed|20889742}}
  
 
* '''Protein family:'''
 
* '''Protein family:'''
  
* '''Paralogous protein(s):'''
+
* '''Paralogous protein(s):''' [[YonR]], [[Xre]]
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===
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=References=
 
=References=
 
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<pubmed>20889742 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 17:18, 11 October 2010

Gene name yqaE
Synonyms
Essential no
Product unknown
Function unknown
MW, pI 13 kDa, 5.42
Gene length, protein length 348 bp, 116 aa
Immediate neighbours yqaF, yqaD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YqaE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU26350

Phenotypes of a mutant

  • essential in the wild type background (due to overexpression of the toxic proteins YqaH and YqaM) PubMed
  • no phenotype if deleted with the complete skin element PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Tatsu Kimura, Yukie Amaya, Kazuo Kobayashi, Naotake Ogasawara, Tsutomu Sato
Repression of sigK intervening (skin) element gene expression by the CI-like protein SknR and effect of SknR depletion on growth of Bacillus subtilis cells.
J Bacteriol: 2010, 192(23);6209-16
[PubMed:20889742] [WorldCat.org] [DOI] (I p)