YncF

• Description: dUTP diphosphatase
  
  

Gene name	yncF
Synonyms
Essential	no
Product	dUTP diphosphatase
Function	nucleotide metabolism
MW, pI	16 kDa, 5.098
Gene length, protein length	432 bp, 144 aa
Immediate neighbours	yncE, cotU
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU17660

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

nucleotide metabolism/ other

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): YosS

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2XCD; 2XCE (complex with dUpnhpp)

• UniProt: O31801

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Javier García-Nafría, Lynn Burchell, Mine Takezawa, Neil J Rzechorzek, Mark J Fogg, Keith S Wilson
The structure of the genomic Bacillus subtilis dUTPase: novel features in the Phe-lid.
Acta Crystallogr D Biol Crystallogr: 2010, 66(Pt 9);953-61
[PubMed:20823546] [WorldCat.org] [DOI] (I p)

Gui Lan Li, Juan Wang, Lan Fen Li, Xiao Dong Su
Crystallization and preliminary X-ray analysis of three dUTPases from Gram-positive bacteria.
Acta Crystallogr Sect F Struct Biol Cryst Commun: 2009, 65(Pt 4);339-42
[PubMed:19342774] [WorldCat.org] [DOI] (I p)