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| − | The phosphorelay is a complex variation of a [[two-component systems|two-component regulatory system]]. It includes phosphotransferases that transfer the phosphoryl group from the sensor kinases to the ultimate target. The sporulation initiation phosphorelay is the paradigm of this class of signal transduction systems.
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| − | ==The kinases==
| + | {{CategoryTree |
| − | * [[KinA]] (controlled by [[Sda]], [[KipI]], and [[KipA]]) | + | |Parents= |
| − | * [[KinB]] (controlled by [[Sda]], [[KbaA]], and [[KapB]]) | + | * 3. [[Information processing]] |
| − | * [[KinC]] | + | ** 3.4. [[Regulation of gene expression]] |
| − | * [[KinD]]
| + | |Neighbours= |
| − | * [[KinE]]
| + | * 3.4.1. [[Sigma factors and their control]] |
| − | | + | * 3.4.2. [[Transcription factors and their control]] |
| − | ==The phosphotransferases==
| + | * 3.4.3. [[Trigger enzymes]] |
| − | * [[Spo0F]] | + | * 3.4.4. [[RNA binding regulators]] |
| − | * [[Spo0B]]
| + | * 3.4.5. [[Regulators of core metabolism]] |
| − | | + | * 3.4.6. [[Transition state regulators]] |
| − | ==The ultimate target==
| + | * 3.4.7. [[Phosphorelay]] |
| − | * [[Spo0A]] | + | * 3.4.8. [[Quorum sensing]] |
| − | | + | |Related= |
| − | ==Phosphatases controlling the phosphorelay (and peptides that modulate their activity)==
| + | none |
| − | * [[Spo0E]]: dephosphorylation of [[Spo0A]]
| + | |}} |
| − | * [[YisI]]: dephosphorylation of [[Spo0A]] | |
| − | * [[YnzD]]: dephosphorylation of [[Spo0A]] | |
| − | * [[RapA]], [[PhrA]]: dephosphorylation of [[Spo0F]] | |
| − | * [[RapB]]: dephosphorylation of [[Spo0F]] | |
| − | * [[RapE]], [[PhrE]]: dephosphorylation of [[Spo0F]] | |
| − | * [[RapH]]: dephosphorylation of [[Spo0F]] | |
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| − | ==Related lists==
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| − | * [[two-component systems]]
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| − | * [[response regulator aspartate phosphatases]]
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| − | * [[phosphoproteins]]
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| − | * [[protein kinases and phosphatases]]
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| − | ==A mathematical model==
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| − | <pubmed> 20238180 </pubmed>
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| − | ==Reviews==
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| − | <pubmed>8730857 11587783 9778730 1664534 12406209 11489844 10745001 8432743 19995980 19943903 20133180 20154131 </pubmed>
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