Difference between revisions of "CheA"

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(Expression and regulation)
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:''' [[CheA]]-[[McpB]] {{PubMed|19864420}}, [[CheA]]-[[CheC]], [[CheA]]-[[CheY]]
+
* '''Interactions:''' [[CheA]]-[[McpB]] {{PubMed|19864420}}, [[CheA]]-[[CheC]] {{PubMed|11722727}}, [[CheA]]-[[CheY]]
  
 
* '''Localization:''' membrane (according to Swiss-Prot)
 
* '''Localization:''' membrane (according to Swiss-Prot)
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** [[Spo0A]]: transcription repression {{PubMed|14651647}}
 
** [[Spo0A]]: transcription repression {{PubMed|14651647}}
 
** [[CodY]]: transcription repression {{PubMed|12730172}}
 
** [[CodY]]: transcription repression {{PubMed|12730172}}
 +
** [[DegU]] (non-phosphorylated): transcription activation {{PubMed|17850253}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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<pubmed> 20122866  </pubmed>
 
<pubmed> 20122866  </pubmed>
 
==Original publications==
 
==Original publications==
<pubmed>1938941,12123464,17908686,8866475,12094812,10094672,11722727,14651647, 9657996,8157612,15175317 9721285 </pubmed>
+
<pubmed>1938941,12123464,17908686,8866475,12094812,10094672,11722727,14651647, 9657996,8157612,15175317 9721285 17850253 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 18:17, 31 July 2010

  • Description: two-component sensor kinase, chemotactic signal modulator

Gene name cheA
Synonyms cheN
Essential no
Product two-component sensor kinase
Function chemotactic signal modulator
MW, pI 74 kDa, 4.452
Gene length, protein length 2013 bp, 671 aa
Immediate neighbours cheB, cheW
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CheA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU16430

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of CheY
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications