Difference between revisions of "YloS"
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=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' [http://www. | + | * '''Structure:''' [http://www.pdb.org/pdb/explore/explore.do?structureId=3LM8 3LM8] |
* '''UniProt:''' [http://www.uniprot.org/uniprot/O34664 O34664] | * '''UniProt:''' [http://www.uniprot.org/uniprot/O34664 O34664] | ||
Revision as of 18:17, 7 July 2010
- Description: thiamine pyrophosphokinase
| Gene name | yloS |
| Synonyms | thiN |
| Essential | no |
| Product | thiamine pyrophosphokinase |
| Function | thiamine salvage |
| Metabolic function and regulation of this protein in SubtiPathways: Thiamin | |
| MW, pI | 23 kDa, 5.216 |
| Gene length, protein length | 642 bp, 214 aa |
| Immediate neighbours | rpe, spoVM |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU15800
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + thiamine = AMP + thiamine diphosphate (according to Swiss-Prot)
- Protein family: thiamine pyrophosphokinase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 3LM8
- UniProt: O34664
- KEGG entry: [2]
- E.C. number: 2.7.6.2
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Christopher T Jurgenson, Tadhg P Begley, Steven E Ealick
The structural and biochemical foundations of thiamin biosynthesis.
Annu Rev Biochem: 2009, 78;569-603
[PubMed:19348578]
[WorldCat.org]
[DOI]
(I p)
Original publications
