Difference between revisions of "Noc"

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= Categories containing this gene/protein =
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{{SubtiWiki category|[[cell division]]}}
 
=The protein=
 
=The protein=
  

Revision as of 18:25, 30 November 2010

  • Description: DNA-binding protein, spatial regulator of cell division to protect the nucleoid, and timing device with an important role in the coordination of chromosome segregation and cell division

Gene name noc
Synonyms yyaA
Essential no
Product effector of nucleoid occlusion
Function control of cell division
MW, pI 32 kDa, 5.812
Gene length, protein length 849 bp, 283 aa
Immediate neighbours yyaB, rsmG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YyaA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU40990

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

cell division

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds specific sites on the chromosome PubMed
  • Protein family: ParB family (according to Swiss-Prot)
  • Paralogous protein(s): Spo0J

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
    • ComK: transcription activation PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Jeff Errington, Newcastle, UK Homepage

Your additional remarks

References

Reviews

Marc Bramkamp, Suey van Baarle
Division site selection in rod-shaped bacteria.
Curr Opin Microbiol: 2009, 12(6);683-8
[PubMed:19884039] [WorldCat.org] [DOI] (I p)

David W Adams, Jeff Errington
Bacterial cell division: assembly, maintenance and disassembly of the Z ring.
Nat Rev Microbiol: 2009, 7(9);642-53
[PubMed:19680248] [WorldCat.org] [DOI] (I p)

Original Publications