YxaM

• Description: similar to antibiotic resistance protein
  
  

Gene name	yxaM
Synonyms
Essential	no
Product	unknown
Function	unknown
Metabolic function and regulation of this protein in SubtiPathways: Asp, Asn
MW, pI	44 kDa, 8.306
Gene length, protein length	1197 bp, 399 aa
Immediate neighbours	asnH, yxaL
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU39930

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

resistance against toxins/ antibiotics, membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: major facilitator superfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P42112

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yxbB-yxbA-yxnB-asnH-yxaM PubMed

• Sigma factor:

• Regulation:
  • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • repressed during logrithmic growth (AbrB) PubMed

• Regulatory mechanism:
  • CodY: transcription repression PubMed
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: