Difference between revisions of "PtpZ"
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| − | * '''Description:''' | + | * '''Description:''' phosphotyrosine protein phosphatase, antagonist to [[PtkA]] <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || phosphotyrosine protein phosphatase, <br/>antagonist to [[PtkA]] |
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|style="background:#ABCDEF;" align="center"|'''Function''' || protein tyrosine dephosphorylation | |style="background:#ABCDEF;" align="center"|'''Function''' || protein tyrosine dephosphorylation | ||
Revision as of 14:20, 9 May 2010
- Description: phosphotyrosine protein phosphatase, antagonist to PtkA
| Gene name | ptpZ |
| Synonyms | ywqE |
| Essential | no |
| Product | phosphotyrosine protein phosphatase, antagonist to PtkA |
| Function | protein tyrosine dephosphorylation |
| MW, pI | 28 kDa, 6.66 |
| Gene length, protein length | 762 bp, 254 aa |
| Immediate neighbours | ywqF, ptkA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU36240
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate (according to Swiss-Prot)
- Protein family: cpsB/capC family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P96717
- KEGG entry: [2]
- E.C. number: 3.1.3.48
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ivan Mijakovic, Lucia Musumeci, Lutz Tautz, Dina Petranovic, Robert A Edwards, Peter Ruhdal Jensen, Tomas Mustelin, Josef Deutscher, Nunzio Bottini
In vitro characterization of the Bacillus subtilis protein tyrosine phosphatase YwqE.
J Bacteriol: 2005, 187(10);3384-90
[PubMed:15866923]
[WorldCat.org]
[DOI]
(P p)
Ivan Mijakovic, Sandrine Poncet, Grégory Boël, Alain Mazé, Sylvie Gillet, Emmanuel Jamet, Paulette Decottignies, Christophe Grangeasse, Patricia Doublet, Pierre Le Maréchal, Josef Deutscher
Transmembrane modulator-dependent bacterial tyrosine kinase activates UDP-glucose dehydrogenases.
EMBO J: 2003, 22(18);4709-18
[PubMed:12970183]
[WorldCat.org]
[DOI]
(P p)
