Difference between revisions of "YxdL"

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* '''Description:''' similar to [[ABC transporter]] (ATP-binding protein) <br/><br/>
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* '''Description:''' [[ABC transporter]] (ATP-binding protein) <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Product''' || [[ABC transporter]] (ATP-binding protein)
 
|style="background:#ABCDEF;" align="center"| '''Product''' || [[ABC transporter]] (ATP-binding protein)
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+
|style="background:#ABCDEF;" align="center"|'''Function''' || export of toxic peptides
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 28 kDa, 7.365   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 28 kDa, 7.365   
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=References=
 
=References=
  
<pubmed>17600057,10092453,15289557,</pubmed>
+
<pubmed>17600057,10092453,15289557, 21078927 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 17:54, 17 November 2010

Gene name yxdL
Synonyms
Essential no
Product ABC transporter (ATP-binding protein)
Function export of toxic peptides
MW, pI 28 kDa, 7.365
Gene length, protein length 771 bp, 257 aa
Immediate neighbours yxdM, yxdK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YxdL context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU39640

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ABC transporter family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: membrane associated (via YxdM) PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism: YxdJ: transcription activation PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Anna Staroń, Dora Elisabeth Finkeisen, Thorsten Mascher
Peptide antibiotic sensing and detoxification modules of Bacillus subtilis.
Antimicrob Agents Chemother: 2011, 55(2);515-25
[PubMed:21078927] [WorldCat.org] [DOI] (I p)

Hanne-Leena Hyyryläinen, Milla Pietiäinen, Tuula Lundén, Anna Ekman, Marika Gardemeister, Sanna Murtomäki-Repo, Haike Antelmann, Michael Hecker, Leena Valmu, Matti Sarvas, Vesa P Kontinen
The density of negative charge in the cell wall influences two-component signal transduction in Bacillus subtilis.
Microbiology (Reading): 2007, 153(Pt 7);2126-2136
[PubMed:17600057] [WorldCat.org] [DOI] (P p)

Pascale Joseph, Annick Guiseppi, Alexei Sorokin, François Denizot
Characterization of the Bacillus subtilis YxdJ response regulator as the inducer of expression for the cognate ABC transporter YxdLM.
Microbiology (Reading): 2004, 150(Pt 8);2609-2617
[PubMed:15289557] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)