Difference between revisions of "YocH"
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| − | * '''Description:''' | + | * '''Description:''' peptidoglycan hydrolase (amidase) <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || peptidoglycan hydrolase |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || cell wall turnover |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 30 kDa, 8.371 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 30 kDa, 8.371 | ||
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* '''Interactions:''' | * '''Interactions:''' | ||
| − | * '''Localization:''' | + | * '''Localization:''' extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed] |
=== Database entries === | === Database entries === | ||
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** expressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed] | ** expressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed] | ||
** repressed during logrithmic growth ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/15101989 PubMed] | ** repressed during logrithmic growth ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/15101989 PubMed] | ||
| + | ** induced in response to cell wall derived muropeptides derived from growing cells but not lysed cells (requires activities of [[PrkC]] and [[YocH]]) {{PubMed|20070526}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
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=References= | =References= | ||
| − | <pubmed>14651647,15101989,18957862,12950927, 20059685 </pubmed> | + | <pubmed>14651647,15101989,18957862,12950927, 20059685 20070526 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:17, 15 January 2010
- Description: peptidoglycan hydrolase (amidase)
| Gene name | yocH |
| Synonyms | |
| Essential | no |
| Product | peptidoglycan hydrolase |
| Function | cell wall turnover |
| MW, pI | 30 kDa, 8.371 |
| Gene length, protein length | 861 bp, 287 aa |
| Immediate neighbours | desR, yocI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU19210
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: extracellular (signal peptide) PubMed
Database entries
- Structure:
- UniProt: O34669
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: yocH PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: AH024 knock-out mutant (kan) available in the lab of Kevin Devine
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
