YvgN

• Description: glyoxal reductase, general stress protein
  
  

Gene name	yvgN
Synonyms	yvsB
Essential	no
Product	glyoxal reductase
Function	unknown
MW, pI	31 kDa, 5.066
Gene length, protein length	828 bp, 276 aa
Immediate neighbours	yvgM, yvgO
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU33400

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Lactaldehyde + NADP⁺ = methylglyoxal + NADPH (according to Swiss-Prot)

• Protein family: aldo/keto reductase family (according to Swiss-Prot)

• Paralogous protein(s): YtbE

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 3B3E

• UniProt: O32210

• KEGG entry: [2]

• E.C. number: 1.1.1.283

Expression and regulation

• Operon:

• Sigma factor: SigB PubMed

• Regulation: induced by stress (SigB) PubMed, repressed by SinR PubMed
  • repressed by SinR PubMed

• Regulatory mechanism:
  • SinR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: