Difference between revisions of "RapE"

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* '''Description:''' response regulator aspartate phosphatase, dephosphorylates [[Spo0F]]-P, control of the [[phosphorelay]] <br/><br/>
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* '''Description:''' [[response regulator aspartate phosphatase]], dephosphorylates [[Spo0F]]-P, control of the [[phosphorelay]] <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase
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|style="background:#ABCDEF;" align="center"| '''Product''' || [[response regulator aspartate phosphatase]]
 
|-
 
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation

Revision as of 20:10, 29 November 2009

Gene name rapE
Synonyms yqcH
Essential no
Product response regulator aspartate phosphatase
Function control of sporulation initiation
MW, pI 44 kDa, 7.313
Gene length, protein length 1125 bp, 375 aa
Immediate neighbours yqcI, phrE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RapE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU25830

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: RAP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Virginie Molle, Yoshiko Nakaura, Robert P Shivers, Hirotake Yamaguchi, Richard Losick, Yasutaro Fujita, Abraham L Sonenshein
Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis.
J Bacteriol: 2003, 185(6);1911-22
[PubMed:12618455] [WorldCat.org] [DOI] (P p)

R S McQuade, N Comella, A D Grossman
Control of a family of phosphatase regulatory genes (phr) by the alternate sigma factor sigma-H of Bacillus subtilis.
J Bacteriol: 2001, 183(16);4905-9
[PubMed:11466295] [WorldCat.org] [DOI] (P p)

M Jiang, R Grau, M Perego
Differential processing of propeptide inhibitors of Rap phosphatases in Bacillus subtilis.
J Bacteriol: 2000, 182(2);303-10
[PubMed:10629174] [WorldCat.org] [DOI] (P p)