YtrD

• Description: acetoin ABC transporter (hydrophobic protein, probably channel protein)
  
  

Gene name	ytrD
Synonyms
Essential	no
Product	acetoin ABC transporter (hydrophobic protein, probably channel protein)
Function	uptake of acetoin
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism
MW, pI	36 kDa, 9.094
Gene length, protein length	975 bp, 325 aa
Immediate neighbours	ytrE, ytrC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU30430

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC-5 integral membrane protein family (according to Swiss-Prot)

• Paralogous protein(s): YtrC

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YtrB-(YtrC-YtrD) PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O34953

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ytrA-ytrB-ytrC-ytrD-ytrE-ytrF PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • expressed early in the stationary phase PubMed

• Regulatory mechanism:
  • YtrA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

K I Yoshida, Y Fujita, S D Ehrlich
An operon for a putative ATP-binding cassette transport system involved in acetoin utilization of Bacillus subtilis.
J Bacteriol: 2000, 182(19);5454-61
[PubMed:10986249] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)