Difference between revisions of "CotB"
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* '''Operon:''' | * '''Operon:''' | ||
− | * '''[[Sigma factor]]:''' [[SigK]] {{PubMed|15699190}} | + | * '''[[Sigma factor]]:''' [[SigK]] {{PubMed|15699190,1691789}} |
* '''Regulation:''' | * '''Regulation:''' | ||
+ | ** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|15699190,1691789}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
+ | ** [[GerE]]: transcription activation {{PubMed|1518043}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Line 118: | Line 120: | ||
=References= | =References= | ||
− | <pubmed> 19933362,1518043,2821284,14762006,1691789, 19933362 </pubmed> | + | <pubmed> 19933362,1518043,2821284,14762006,1691789, 19933362 15699190</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 21:48, 29 January 2010
- Description: spore coat protein (outer)
Gene name | cotB |
Synonyms | |
Essential | no |
Product | spore coat protein (outer) |
Function | resistance of the spore |
MW, pI | 42 kDa, 9.831 |
Gene length, protein length | 1140 bp, 380 aa |
Immediate neighbours | ywrJ, cotH |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU36050
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: outer spore coat, at the middle of the spore as a ring- or spiral-like structure PubMed
Database entries
- Structure:
- UniProt: P07789
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Daisuke Imamura, Ritsuko Kuwana, Hiromu Takamatsu, Kazuhito Watabe
Localization of proteins to different layers and regions of Bacillus subtilis spore coats.
J Bacteriol: 2010, 192(2);518-24
[PubMed:19933362]
[WorldCat.org]
[DOI]
(I p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Rita Zilhão, Mónica Serrano, Rachele Isticato, Ezio Ricca, Charles P Moran, Adriano O Henriques
Interactions among CotB, CotG, and CotH during assembly of the Bacillus subtilis spore coat.
J Bacteriol: 2004, 186(4);1110-9
[PubMed:14762006]
[WorldCat.org]
[DOI]
(P p)
L Zheng, R Halberg, S Roels, H Ichikawa, L Kroos, R Losick
Sporulation regulatory protein GerE from Bacillus subtilis binds to and can activate or repress transcription from promoters for mother-cell-specific genes.
J Mol Biol: 1992, 226(4);1037-50
[PubMed:1518043]
[WorldCat.org]
[DOI]
(P p)
L B Zheng, R Losick
Cascade regulation of spore coat gene expression in Bacillus subtilis.
J Mol Biol: 1990, 212(4);645-60
[PubMed:1691789]
[WorldCat.org]
[DOI]
(P p)
W Donovan, L B Zheng, K Sandman, R Losick
Genes encoding spore coat polypeptides from Bacillus subtilis.
J Mol Biol: 1987, 196(1);1-10
[PubMed:2821284]
[WorldCat.org]
[DOI]
(P p)