Difference between revisions of "DgkA"
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=== Additional information=== | === Additional information=== | ||
| − | + | The gene is annotated in KEGG/MetaCyc/Swiss-Prot as diacylglycerol kinase EC 2.7.1.107. However, in the recently published paper (July 2007) by Jerga et al {{PubMed|17535816}}, the authors confirmed that ''dgkA'' is not a diacylglycerol kinase (DagK) but rather an undecaprenol kinase. This annotation was removed from Swiss-Prot as of November 2009. {{PubMed|19935659}} | |
=Expression and regulation= | =Expression and regulation= | ||
Revision as of 11:34, 26 November 2009
- Description: undecaprenol kinase
| Gene name | dgkA |
| Synonyms | yqxF |
| Essential | no |
| Product | undecaprenol kinase |
| Function | biosynthesis of peptidoglycan |
| MW, pI | 12 kDa, 7.128 |
| Gene length, protein length | 342 bp, 114 aa |
| Immediate neighbours | cdd, yqfG |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU25310
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: bacterial diacylglycerol kinase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P19638
- KEGG entry: [2]
- E.C. number: 2.7.1.107
Additional information
The gene is annotated in KEGG/MetaCyc/Swiss-Prot as diacylglycerol kinase EC 2.7.1.107. However, in the recently published paper (July 2007) by Jerga et al PubMed, the authors confirmed that dgkA is not a diacylglycerol kinase (DagK) but rather an undecaprenol kinase. This annotation was removed from Swiss-Prot as of November 2009. PubMed
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Agoston Jerga, Ying-Jie Lu, Gustavo E Schujman, Diego de Mendoza, Charles O Rock
Identification of a soluble diacylglycerol kinase required for lipoteichoic acid production in Bacillus subtilis.
J Biol Chem: 2007, 282(30);21738-45
[PubMed:17535816]
[WorldCat.org]
[DOI]
(P p)
Samuel Amiteye, Kazuo Kobayashi, Daisuke Imamura, Shigeo Hosoya, Naotake Ogasawara, Tsutomu Sato
Bacillus subtilis diacylglycerol kinase (DgkA) enhances efficient sporulation.
J Bacteriol: 2003, 185(17);5306-9
[PubMed:12923107]
[WorldCat.org]
[DOI]
(P p)
