AdhB

• Description: forespore-specific protein, similar to alcohol dehydrogenase
  
  

Gene name	adhB
Synonyms
Essential	no
Product	unknown
Function	unknown
MW, pI	41 kDa, 5.659
Gene length, protein length	1134 bp, 378 aa
Immediate neighbours	yraF, yraE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU26970

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: Class-III subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: spore wall (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O06012

• KEGG entry: [3]

• E.C. number:

Additional information

The gene is annotated in KEGG as alcohol dehydrogenase EC 1.1.1.284. It is annotated in Swiss-Prot as “NAD alcohol dehydrogenase”. It is marked as “alcohol dehydrogenase” in MetaCyc. No literature/experimental evidence supporting the annotation is available. PubMed

Expression and regulation

• Operon: yraG-yraF-adhB-yraE-yraD PubMed

• Sigma factor: SigG PubMed

• Regulation:
  • expressed during sporulation in the forespore (SigG) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325] [WorldCat.org] [DOI] (P p)