Difference between revisions of "LicB"

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(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[licB]]-[[licC]]-[[licA]]-[[licH]]'' {{PubMed|8990303}}
  
* '''Operon:''' ''[[licB]]-[[licC]]-[[licA]]-[[licH]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/8990303 PubMed]
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* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8990303}}
  
* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/8990303 PubMed]
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* '''Regulation:'''  
 +
** carbon catabolite repression ([[CcpA]]) {{PubMed|8990303}}
 +
** induction by oligomeric ß-glucosides ([[LicR]]){{PubMed|8990303}}
  
* '''Regulation:''' repressed by glucose ([[CcpA]]) ,  carbon catabolite repression, induction by oligomeric ß-glucosides [http://www.ncbi.nlm.nih.gov/sites/entrez/8990303 PubMed]
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* '''Regulatory mechanism:'''  
 
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** [[CcpA]]: transcription repression {{PubMed|8990303}}
* '''Regulatory mechanism:''' [[CcpA]]: transcription repression,  catabolite repression: repression by [[CcpA]], induction: transcription activation by the PRD-type regulator [[LicR]] [http://www.ncbi.nlm.nih.gov/sites/entrez/8990303 PubMed]
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** [[LicR]]: transcription activation {{PubMed|8990303}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 10:24, 6 February 2010

Gene name licB
Synonyms celA
Essential no
Product trigger enzyme: lichenan-specific
phosphotransferase system, EIIB component
Function lichenan uptake and phosphorylation,
control of LicR activity
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 10 kDa, 6.314
Gene length, protein length 306 bp, 102 aa
Immediate neighbours licC, licR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
LicB context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU38590

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot)
  • Protein family: PTS permease, lactose permease (Lac) family PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation on Ser-37 PubMed
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References