Difference between revisions of "AroC"

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(Database entries)
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=== Database entries ===
 
=== Database entries ===
  
* '''Structure:'''
+
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1GQN 1GQN] (from ''Salmonella typhi'', 55% identity, 70% similarity) {{PubMed|11976491}}
  
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P35146 P35146]
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P35146 P35146]

Revision as of 11:03, 19 February 2010

  • Description: 3-dehydroquinate dehydratase

Gene name aroC
Synonyms
Essential no
Product 3-dehydroquinate dehydratase
Function biosynthesis of aromatic amino acids
Metabolic function and regulation of this protein in SubtiPathways:
Phe, Tyr, Trp
MW, pI 27 kDa, 4.898
Gene length, protein length 765 bp, 255 aa
Immediate neighbours serA, rsiX
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AroC context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU23080

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 3-dehydroquinate = 3-dehydroshikimate + H2O (according to Swiss-Prot)
  • Protein family: type-I 3-dehydroquinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1GQN (from Salmonella typhi, 55% identity, 70% similarity) PubMed
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References