Difference between revisions of "NrdI"

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(Expression and regulation)
(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[nrdI]]-[[nrdE]]-[[nrdF]]-[[ymaB]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/16885274 PubMed]
+
* '''Operon:''' ''[[nrdI]]-[[nrdE]]-[[nrdF]]-[[ymaB]]'' {{PubMed|16885274}}
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|16885274}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** distinct promoters for aerobic and anaerobic expression [http://www.ncbi.nlm.nih.gov/sites/entrez/16885274 PubMed]
+
** expressed under anaerobic conditions ([[ResD]]) {{PubMed|16885274}}
** expressed under anaerobic conditions ([[ResD]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/16885274 PubMed]
 
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[ResD]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/16885274 PubMed]
+
** [[ResD]]: transcription activation {{PubMed|16885274}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 20:16, 16 October 2009

  • Description: ribonucleoside-diphosphate reductase

Gene name nrdI
Synonyms ymaA
Essential yes PubMed
Product ribonucleoside-diphosphate reductase
Function synthesis of deoxyribonucleoside triphosphates
Metabolic function and regulation of this protein in SubtiPathways:
Nucleotides (regulation)
MW, pI 14 kDa, 8.58
Gene length, protein length 390 bp, 130 aa
Immediate neighbours ymzA, nrdE
Gene sequence (+200bp) Protein sequence
Genetic context
YmaA context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU17370

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: nrdI family (according to Swiss-Prot)
  • Paralogous protein(s): YosM

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under anaerobic conditions (ResD) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References