Difference between revisions of "IspA"
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| − | * '''Description:''' | + | * '''Description:''' geranyltranstransferase<br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || geranyltranstransferase |
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of isoprenoids |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 4.522 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 4.522 | ||
Revision as of 16:52, 3 March 2010
- Description: geranyltranstransferase
| Gene name | ispA |
| Synonyms | |
| Essential | no |
| Product | geranyltranstransferase |
| Function | biosynthesis of isoprenoids |
| MW, pI | 33 kDa, 4.522 |
| Gene length, protein length | 957 bp, 319 aa |
| Immediate neighbours | metE, rsbRB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU13190
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate (according to Swiss-Prot)
- Protein family: FPP/GGPP synthetase family (according to Swiss-Prot) peptidase S8 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P11018
- KEGG entry: [3]
- E.C. number: 2.5.1.10
Additional information
Expression and regulation
- Operon: ispA (according to DBTBS)
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Mattijs K Julsing, Michael Rijpkema, Herman J Woerdenbag, Wim J Quax, Oliver Kayser
Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis.
Appl Microbiol Biotechnol: 2007, 75(6);1377-84
[PubMed:17458547]
[WorldCat.org]
[DOI]
(P p)
Y Koide, A Nakamura, T Uozumi, T Beppu
Cloning and sequencing of the major intracellular serine protease gene of Bacillus subtilis.
J Bacteriol: 1986, 167(1);110-6
[PubMed:3087947]
[WorldCat.org]
[DOI]
(P p)
