Difference between revisions of "ThrS"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[thrS]]'' {{PubMed|8969504}} |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8288542}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** induced by threonine limitation ([[T-box]]) {{PubMed|19258532}} | + | ** induced by threonine limitation ([[T-box]]) {{PubMed|19258532,8288542}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| Line 125: | Line 125: | ||
=References= | =References= | ||
| − | <pubmed>8288542,1379177,19258532,7476165,12136084,,17114254, </pubmed> | + | <pubmed>8288542,1379177,19258532,7476165,12136084,8969504 ,17114254, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 20:31, 17 December 2009
- Description: threonyl-tRNA synthetase (major)
| Gene name | thrS |
| Synonyms | |
| Essential | no |
| Product | threonyl-tRNA synthetase (major) |
| Function | translation |
| Metabolic function and regulation of this protein in SubtiPathways: tRNA charging | |
| MW, pI | 73 kDa, 5.214 |
| Gene length, protein length | 1929 bp, 643 aa |
| Immediate neighbours | ysaA, ytxC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU28950
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr) (according to Swiss-Prot)
- Protein family: class-II aminoacyl-tRNA synthetase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P18255
- KEGG entry: [3]
- E.C. number: 6.1.1.3
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Regulatory mechanism:
- T-box: RNA switch, transcriptional antitermination PubMed
- Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
