Difference between revisions of "CotO"
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| − | * '''Description:''' | + | * '''Description:''' spore coat morphogenetic protein, controls assembly of the coat layers and coat surface topography <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || spore coat morphogenetic protein |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || controls assembly of the coat layers <br/>and coat surface topography |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 25 kDa, 6.376 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 25 kDa, 6.376 | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | spores are defective in germination {{PubMed|16321932}} | ||
=== Database entries === | === Database entries === | ||
Revision as of 18:29, 29 September 2009
- Description: spore coat morphogenetic protein, controls assembly of the coat layers and coat surface topography
| Gene name | cotO |
| Synonyms | yjbX |
| Essential | no |
| Product | spore coat morphogenetic protein |
| Function | controls assembly of the coat layers and coat surface topography |
| MW, pI | 25 kDa, 6.376 |
| Gene length, protein length | 681 bp, 227 aa |
| Immediate neighbours | fabI, cotZ |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU11730
Phenotypes of a mutant
spores are defective in germination PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: spore wall (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O31622
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: cotO (according to DBTBS)
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
D C McPherson, H Kim, M Hahn, R Wang, P Grabowski, P Eichenberger, A Driks
Characterization of the Bacillus subtilis spore morphogenetic coat protein CotO.
J Bacteriol: 2005, 187(24);8278-90
[PubMed:16321932]
[WorldCat.org]
[DOI]
(P p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147]
[WorldCat.org]
[DOI]
(P p)
