Difference between revisions of "LicB"
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| − | * '''Description:''' [[trigger enzymes|trigger enzyme]]: lichenan-specific phosphotransferase system, EIIB component <br/><br/> | + | * '''Description:''' [[trigger enzymes|trigger enzyme]]: lichenan-specific [[PTS|phosphotransferase system]], EIIB component of the [[PTS]]<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || [[trigger enzymes|trigger enzyme]]: lichenan-specific <br/>phosphotransferase system, EIIB component | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[trigger enzymes|trigger enzyme]]: lichenan-specific <br/>[[PTS|phosphotransferase system]], EIIB component |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || lichenan uptake and phosphorylation, <br/>control of LicR activity | |style="background:#ABCDEF;" align="center"|'''Function''' || lichenan uptake and phosphorylation, <br/>control of LicR activity | ||
| Line 56: | Line 56: | ||
* '''Catalyzed reaction/ biological activity:''' Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot) | * '''Catalyzed reaction/ biological activity:''' Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot) | ||
| − | * '''Protein family:''' PTS permease, lactose permease (Lac) family [http://www.ncbi.nlm.nih.gov/pubmed/10627040 PubMed] | + | * '''Protein family:''' [[PTS]] permease, lactose permease (Lac) family [http://www.ncbi.nlm.nih.gov/pubmed/10627040 PubMed] |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
Revision as of 19:27, 24 November 2009
- Description: trigger enzyme: lichenan-specific phosphotransferase system, EIIB component of the PTS
| Gene name | licB |
| Synonyms | celA |
| Essential | no |
| Product | trigger enzyme: lichenan-specific phosphotransferase system, EIIB component |
| Function | lichenan uptake and phosphorylation, control of LicR activity |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 10 kDa, 6.314 |
| Gene length, protein length | 306 bp, 102 aa |
| Immediate neighbours | licC, licR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU38590
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation on Ser-37 PubMed
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P46318
- KEGG entry: [2]
- E.C. number: 2.7.1.69 9
Additional information
Expression and regulation
- Regulation: repressed by glucose (CcpA) , carbon catabolite repression, induction by oligomeric ß-glucosides PubMed
- Regulatory mechanism: CcpA: transcription repression, catabolite repression: repression by CcpA, induction: transcription activation by the PRD-type regulator LicR PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
