Difference between revisions of "RapH"

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(Expression and regulation)
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* '''Description:''' response regulator aspartate phosphatase <br/><br/>
+
* '''Description:''' response regulator aspartate phosphatase, dephosphorylates [[Spo0F]]-P, control of the [[phosphorelay]], control of [[ComA]] activity <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase
 
|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation  
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of sporulation initiation and [[ComA]] activity
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 49 kDa, 6.121   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 49 kDa, 6.121   
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' binds to and thereby inhibits [[ComA]] activity {{PubMed|17581123}}; in addition, RapH dephosphorylates [[Spo0F]]-P and thereby controls the [[phosphorelay]] {{PubMed|17581123}}
  
 
* '''Protein family:''' RAP family (according to Swiss-Prot)
 
* '''Protein family:''' RAP family (according to Swiss-Prot)
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
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* '''Interactions:''' [[RapH]]-[[ComA]] {{PubMed|17581123}}, [[RapH]]-[[Spo0F]]-P {{PubMed|17581123}}
  
 
* '''Localization:'''
 
* '''Localization:'''

Revision as of 11:23, 29 November 2009

  • Description: response regulator aspartate phosphatase, dephosphorylates Spo0F-P, control of the phosphorelay, control of ComA activity

Gene name rapH
Synonyms yeeH, yzqA
Essential no
Product response regulator aspartate phosphatase
Function control of sporulation initiation and ComA activity
MW, pI 49 kDa, 6.121
Gene length, protein length 1293 bp, 431 aa
Immediate neighbours yeeG, yeeI
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RapH context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU06830

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds to and thereby inhibits ComA activity PubMed; in addition, RapH dephosphorylates Spo0F-P and thereby controls the phosphorelay PubMed
  • Protein family: RAP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References