Difference between revisions of "RsbR"
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* '''Modification:''' RsbRA: Thr-171 and Thr-205 | * '''Modification:''' RsbRA: Thr-171 and Thr-205 | ||
− | + | phosphorylation on Thr-171 (RsbRA) [http://www.ncbi.nlm.nih.gov/pubmed/17726680 PubMed] | |
− | |||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
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* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/8002610 PubMed] | * '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/8002610 PubMed] | ||
− | * '''Regulation:''' | + | * '''Regulation:''' constitutively expressed {{PubMed|20019076}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
Line 128: | Line 127: | ||
<pubmed>19704888 16319496 </pubmed> | <pubmed>19704888 16319496 </pubmed> | ||
==Original Articles== | ==Original Articles== | ||
− | <pubmed>8002610,8682769,8682789, 17726680,10781545,15583165, 8824586,10329124,17158665, 9179850,8808936,15312768, 11244072,15342582,, 12950928, 15466036, 9179850, 8955331, 18832644 ,17726680 ,17218307 </pubmed> | + | <pubmed>8002610,8682769,8682789, 17726680,10781545,15583165, 8824586,10329124,17158665, 9179850,8808936,15312768, 11244072,15342582,, 12950928, 15466036, 9179850, 8955331, 18832644 ,17726680 ,17218307 20019076 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 10:53, 19 December 2009
- Description: activator of RsbT kinase activity, part of the stressosome
Gene name | rsbR |
Synonyms | ycxR, rsbRA |
Essential | no |
Product | activator of RsbT kinase activity |
Function | control of SigB activity |
Metabolic function and regulation of this protein in SubtiPathways: Stress | |
MW, pI | 30 kDa, 4.731 |
Gene length, protein length | 822 bp, 274 aa |
Immediate neighbours | ndoA, rsbS |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU04670
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
Extended information on the protein
- Kinetic information:
- Domains: RsbRA is composed of an N-terminal nonheme globin domain and a highly conserved C-terminal STAS (Sulphate Transporter and AntiSigma factor antagonist) domain. The C-terminal STAS domain is the target of the serine/threonine-specific kinase RsbT (see below).
- Modification: RsbRA: Thr-171 and Thr-205
phosphorylation on Thr-171 (RsbRA) PubMed
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- UniProt: P42409
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: constitutively expressed PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Bill Haldenwang, San Antonio, USA
- Chet Price, Davis, USA homepage
- Rick Lewis, Newcastle, UK homepage
Your additional remarks
References
Reviews
Original Articles