Difference between revisions of "DltA"
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=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[dltA]]-[[dltB]]-[[dltC]]-[[dltD]]-[[dltE]]'' {{PubMed|7797557}} | ||
| − | + | * '''[[Sigma factor]]:''' [[SigD]] {{PubMed|7797557}}, [[SigX]] {{PubMed|14762009}} | |
| − | |||
| − | * '''[[Sigma factor]]:''' [[SigD]], [[SigX]] | ||
* '''Regulation:''' | * '''Regulation:''' | ||
** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}} | ** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}} | ||
| − | ** repressed under conditions that trigger sporulation ([[Spo0A]]) | + | ** repressed under conditions that trigger sporulation ([[Spo0A]]) {{PubMed|7797557}} |
| − | * '''Regulatory mechanism:''' activated by [[YvrHb]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed] | + | * '''Regulatory mechanism:''' |
| − | ** [[Spo0A]]: transcription repression | + | ** activated by [[YvrHb]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed] |
| + | ** [[Spo0A]]: transcription repression {{PubMed|7797557}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 10:17, 6 February 2010
- Description: D-alanyl-D-alanine carrier protein ligase
| Gene name | dltA |
| Synonyms | ipa-5r, dae |
| Essential | no |
| Product | D-alanyl-D-alanine carrier protein ligase |
| Function | biosynthesis of teichoic acid |
| MW, pI | 55 kDa, 4.929 |
| Gene length, protein length | 1509 bp, 503 aa |
| Immediate neighbours | menA, dltB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU38500
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + D-alanine + poly(ribitol phosphate) = AMP + diphosphate + O-D-alanyl-poly(ribitol phosphate) (according to Swiss-Prot)
- Protein family: DltA subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 3E7X
- UniProt: P39581
- KEGG entry: [3]
- E.C. number: 6.1.1.13
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Mohamed Marahiel, Marburg University, Germany homepage
Your additional remarks
References
