Difference between revisions of "BofC"
| Line 1: | Line 1: | ||
| − | * '''Description:''' general stress protein, controls processing of pro-SigK by SpoIVFB <br/><br/> | + | * '''Description:''' general stress protein, controls processing of pro-[[SigK]] by [[SpoIVFB]] <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || forespore regulator of the sigma-K checkpoint | |style="background:#ABCDEF;" align="center"| '''Product''' || forespore regulator of the sigma-K checkpoint | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of processing of pro-SigK by SpoIVFB | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of processing of pro-[[SigK]] by [[SpoIVFB]] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 19 kDa, 5.753 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 19 kDa, 5.753 | ||
| Line 92: | Line 92: | ||
* '''[[Sigma factor]]:''' [[SigF]] {{PubMed|15699190}}, [[SigB]] {{PubMed|11544224}} | * '''[[Sigma factor]]:''' [[SigF]] {{PubMed|15699190}}, [[SigB]] {{PubMed|11544224}} | ||
| − | * '''Regulation:''' | + | * '''Regulation:''' |
| + | ** expressed early during sporulation in the forespore ([[SigF]]) {{PubMed|16497325}} | ||
| + | ** induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed] | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
Revision as of 21:25, 31 October 2009
| Gene name | bofC |
| Synonyms | |
| Essential | no |
| Product | forespore regulator of the sigma-K checkpoint |
| Function | control of processing of pro-SigK by SpoIVFB |
| MW, pI | 19 kDa, 5.753 |
| Gene length, protein length | 510 bp, 170 aa |
| Immediate neighbours | ruvA, csbX |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU27750
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure: 2BW2
- UniProt: O05391
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325]
[WorldCat.org]
[DOI]
(P p)
Hayley M Patterson, James A Brannigan, Simon M Cutting, Keith S Wilson, Anthony J Wilkinson, Eiso Ab, Tammo Diercks, Rob N de Jong, Vincent Truffault, Gert E Folkers, Robert Kaptein
The structure of bypass of forespore C, an intercompartmental signaling factor during sporulation in Bacillus.
J Biol Chem: 2005, 280(43);36214-20
[PubMed:16049010]
[WorldCat.org]
[DOI]
(P p)
A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224]
[WorldCat.org]
[DOI]
(P p)
P Wakeley, N T Hoa, S Cutting
BofC negatively regulates SpoIVB-mediated signalling in the Bacillus subtilis sigmaK-checkpoint.
Mol Microbiol: 2000, 36(6);1415-24
[PubMed:10931291]
[WorldCat.org]
[DOI]
(P p)
Manuel Gomez, Simon M Cutting
BofC encodes a putative forespore regulator of the Bacillus subtilis sigma K checkpoint.
Microbiology (Reading): 1997, 143 ( Pt 1);157-170
[PubMed:9025289]
[WorldCat.org]
[DOI]
(P p)
