Difference between revisions of "CotH"

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|style="background:#ABCDEF;" align="center"| '''Product''' || spore coat protein (inner)
 
|style="background:#ABCDEF;" align="center"| '''Product''' || spore coat protein (inner)
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || protection of CotU and CotC in the mother cell
+
|style="background:#ABCDEF;" align="center"|'''Function''' || protection of [[CotU]] and [[CotC]] in the mother cell
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.953   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.953   
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[cotH]]'' {{PubMed|8755863}}
  
* '''[[Sigma factor]]:''' [[SigK]] {{PubMed|15699190}}
+
* '''[[Sigma factor]]:''' [[SigK]] {{PubMed|15699190,8755863}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|15699190,8755863,15470121}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[GerE]]: transcription repression {{PubMed|15470121}}
 +
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
  
<pubmed>10198031,, </pubmed>
+
<pubmed>10198031,15699190,8755863,15470121, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 21:52, 29 January 2010

  • Description: spore coat protein (inner)

Gene name cotH
Synonyms ywrH
Essential no
Product spore coat protein (inner)
Function protection of CotU and CotC in the mother cell
MW, pI 42 kDa, 5.953
Gene length, protein length 1086 bp, 362 aa
Immediate neighbours cotB, cotG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CotH context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU36060

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: cotH family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: spore wall (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK, GerE) PubMed
  • Regulatory mechanism:


  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References