Difference between revisions of "AdhA"
| Line 90: | Line 90: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[adhA]]-[[yraA]]'' {{PubMed|19170879}} |
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** induced in the presence of the toxic carbonyls methylglyoxal and formaldehyde ([[AdhR]]) {{PubMed|19170879}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[AdhR]]: transcription activation {{PubMed|19170879}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 20:28, 25 November 2009
- Description: thiol-dependent aldehyde dehydrogenase, repair of damaged thiol-containing proteins
| Gene name | adhA |
| Synonyms | |
| Essential | no |
| Product | thiol-dependent aldehyde dehydrogenase, reduction of aldehydes |
| Function | response to toxic formaldehyde |
| MW, pI | 37 kDa, 5.367 |
| Gene length, protein length | 1047 bp, 349 aa |
| Immediate neighbours | adhR, yraA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU27010
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: C0SPA5
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
