GerBC

• Description: Nutrient receptor
  
  

Gene name	gerBC
Synonyms
Essential	no
Product	Nutrient receptor
Function	germination
MW, pI	42 kDa, 9.06
Gene length, protein length	1122 bp, 374 aa
Immediate neighbours	gerBB, ywtG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU35820

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: gerABKC lipoprotein family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P39571

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor: SigG PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Swaroopa Atluri, Katerina Ragkousi, Donna E Cortezzo, Peter Setlow
Cooperativity between different nutrient receptors in germination of spores of Bacillus subtilis and reduction of this cooperativity by alterations in the GerB receptor.
J Bacteriol: 2006, 188(1);28-36
[PubMed:16352818] [WorldCat.org] [DOI] (P p)

Takao Igarashi, Peter Setlow
Interaction between individual protein components of the GerA and GerB nutrient receptors that trigger germination of Bacillus subtilis spores.
J Bacteriol: 2005, 187(7);2513-8
[PubMed:15774895] [WorldCat.org] [DOI] (P p)

Rosa-Martha Cabrera-Martinez, Federico Tovar-Rojo, Venkata Ramana Vepachedu, Peter Setlow
Effects of overexpression of nutrient receptors on germination of spores of Bacillus subtilis.
J Bacteriol: 2003, 185(8);2457-64
[PubMed:12670969] [WorldCat.org] [DOI] (P p)

B M Corfe, A Moir, D Popham, P Setlow
Analysis of the expression and regulation of the gerB spore germination operon of Bacillus subtilis 168.
Microbiology (Reading): 1994, 140 ( Pt 11);3079-83
[PubMed:7812448] [WorldCat.org] [DOI] (P p)