Difference between revisions of "EbrB"

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* '''Description:''' multidrug resistance protein <br/><br/>
+
* '''Description:''' multidrug efflux transporter<br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || multidrug resistance protein
+
|style="background:#ABCDEF;" align="center"| '''Product''' || multidrug efflux transporter
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || multidrug resistance  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || multidrug resistance  
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* '''Protein family:'''
 
* '''Protein family:'''
  
* '''Paralogous protein(s):'''
+
* '''Paralogous protein(s):''' [[EbrA]]
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
+
* '''Interactions:''' [[EbrA]]-[[EbrB]] {{PubMed|17417881}}
  
* '''Localization:''' cell membrane (according to Swiss-Prot)
+
* '''Localization:''' cell membrane {{PubMed|17417881}}
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
 
+
<pubmed> 17417881 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:58, 28 December 2009

  • Description: multidrug efflux transporter

Gene name ebrB
Synonyms
Essential no
Product multidrug efflux transporter
Function multidrug resistance
MW, pI 12 kDa, 6.925
Gene length, protein length 351 bp, 117 aa
Immediate neighbours ymaD, ebrA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
EbrB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU17290

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): EbrA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Zhongge Zhang, Che Ma, Owen Pornillos, Xia Xiu, Geoffrey Chang, Milton H Saier
Functional characterization of the heterooligomeric EbrAB multidrug efflux transporter of Bacillus subtilis.
Biochemistry: 2007, 46(17);5218-25
[PubMed:17417881] [WorldCat.org] [DOI] (P p)