Difference between revisions of "GerKA"
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[gerKA]]-[[gerKC]]-[[gerKB]]'' (according to [http://dbtbs.hgc.jp/COG/prom/gerKACB.html DBTBS]) |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' SigG {{PubMed|16707705}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed during sporulation ([[SigG]], [[SpoVT]]) {{PubMed|16707705}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[SpoVT]]: transcription repression {{PubMed|16707705}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 19:03, 19 August 2009
- Description: nutrient receptor
| Gene name | gerKA |
| Synonyms | |
| Essential | no |
| Product | nutrient receptor |
| Function | germination response to the combination of glucose, fructose, aspartate, and KCl |
| MW, pI | 60 kDa, 5.206 |
| Gene length, protein length | 1632 bp, 544 aa |
| Immediate neighbours | yczF, gerKC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU03700
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: gerABKA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P49939
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor: SigG PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Krzysztof Hinc, Krzysztofa Nagórska, Adam Iwanicki, Grzegorz Wegrzyn, Simone J Séror, Michal Obuchowski
Expression of genes coding for GerA and GerK spore germination receptors is dependent on the protein phosphatase PrpE.
J Bacteriol: 2006, 188(12);4373-83
[PubMed:16740944]
[WorldCat.org]
[DOI]
(P p)
Takao Igarashi, Peter Setlow
Transcription of the Bacillus subtilis gerK operon, which encodes a spore germinant receptor, and comparison with that of operons encoding other germinant receptors.
J Bacteriol: 2006, 188(11);4131-6
[PubMed:16707705]
[WorldCat.org]
[DOI]
(P p)
Swaroopa Atluri, Katerina Ragkousi, Donna E Cortezzo, Peter Setlow
Cooperativity between different nutrient receptors in germination of spores of Bacillus subtilis and reduction of this cooperativity by alterations in the GerB receptor.
J Bacteriol: 2006, 188(1);28-36
[PubMed:16352818]
[WorldCat.org]
[DOI]
(P p)
