Difference between revisions of "TatAD"

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(Extended information on the protein)
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:''' [[TatAD]]-[[PhoD]],  [[TatAD]]-[[TatCD]], [[TatAD]]-[[TatCY]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19395490 PubMed]
+
* '''Interactions:''' [[TatAD]]-[[PhoD]] {{PubMed|12867413}},  [[TatAD]]-[[TatCD]], [[TatAD]]-[[TatCY]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19395490 PubMed]
  
 
* '''Localization:''' membrane (according to Swiss-Prot),  forms foci at the division sites and cell poles, localization requires interaction with [[TatCD]] or [[TatCY]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19395490 PubMed]
 
* '''Localization:''' membrane (according to Swiss-Prot),  forms foci at the division sites and cell poles, localization requires interaction with [[TatCD]] or [[TatCY]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19395490 PubMed]

Revision as of 16:56, 13 February 2010

  • Description: component of the TatAdCd twin-arginine translocase

Gene name tatAD
Synonyms yczB
Essential no
Product component of the twin-arginine
translocation pathway
Function protein secretion
MW, pI 7 kDa, 9.693
Gene length, protein length 210 bp, 70 aa
Immediate neighbours phoD, tatCD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TatAD context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU02630

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: translocation of PhoD PubMed
  • Protein family: tatA/E family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: membrane (according to Swiss-Prot), forms foci at the division sites and cell poles, localization requires interaction with TatCD or TatCY PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • expressed under conditions of phosphate limitation (PhoP) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Oscar Kuipers, University of Groningen, The Netherlands Homepage

Your additional remarks

References

Anja N J A Ridder, Esther J de Jong, Jan D H Jongbloed, Oscar P Kuipers
Subcellular localization of TatAd of Bacillus subtilis depends on the presence of TatCd or TatCy.
J Bacteriol: 2009, 191(13);4410-8
[PubMed:19395490] [WorldCat.org] [DOI] (I p)

Jan D H Jongbloed, Ulrike Grieger, Haike Antelmann, Michael Hecker, Reindert Nijland, Sierd Bron, Jan Maarten van Dijl
Two minimal Tat translocases in Bacillus.
Mol Microbiol: 2004, 54(5);1319-25
[PubMed:15554971] [WorldCat.org] [DOI] (P p)

Ovidiu I Pop, Martin Westermann, Rudolf Volkmer-Engert, Daniela Schulz, Cornelius Lemke, Sandra Schreiber, Roman Gerlach, Reinhard Wetzker, Jörg P Müller
Sequence-specific binding of prePhoD to soluble TatAd indicates protein-mediated targeting of the Tat export in Bacillus subtilis.
J Biol Chem: 2003, 278(40);38428-36
[PubMed:12867413] [WorldCat.org] [DOI] (P p)

J D Jongbloed, U Martin, H Antelmann, M Hecker, H Tjalsma, G Venema, S Bron, J M van Dijl, J Müller
TatC is a specificity determinant for protein secretion via the twin-arginine translocation pathway.
J Biol Chem: 2000, 275(52);41350-7
[PubMed:11007775] [WorldCat.org] [DOI] (P p)