Difference between revisions of "UreC"

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* '''Structure:'''
 
* '''Structure:'''
  
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P77837 P77837]
+
* '''UniProt:''' [http://www.uniprot.org/uniprot/P77837 P77837]
  
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU36640]
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU36640]

Revision as of 14:56, 20 July 2009

  • Description: urease (alpha subunit)

Gene name ureC
Synonyms
Essential no
Product urease (alpha subunit)
Function utilization of urea as alternative nitrogen source
Metabolic function and regulation of this protein in SubtiPathways:
Purine catabolism, Ammonium/ glutamate
MW, pI 61 kDa, 5.091
Gene length, protein length 1707 bp, 569 aa
Immediate neighbours ywnA, ureB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
UreC context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU36640

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Urea + H2O = CO2 + 2 NH3 (according to Swiss-Prot)
  • Protein family: urease family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation: induced by nitrogen limitation (GlnR, TnrA) PubMed, repressed by CodY PubMed
    • expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
    • induced in the presence of purine nucleotides (inducer: allantoin) (PucR) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References