Difference between revisions of "MalA"

From SubtiWiki
Jump to: navigation, search
Line 80: Line 80:
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1U8X 1U8X]
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1U8X 1U8X]
  
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P54716 P54716]
+
* '''UniProt:''' [http://www.uniprot.org/uniprot/P54716 P54716]
  
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU08180]
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU08180]

Revision as of 11:35, 20 July 2009

  • Description: 6-phospho-alpha-glucosidase

Gene name malA
Synonyms glvG, glvA
Essential no
Product 6-phospho-alpha-glucosidase
Function maltose utilization
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 50 kDa, 4.74
Gene length, protein length 1347 bp, 449 aa
Immediate neighbours yfjA, glvR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MalA context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU08180

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Maltose 6'-phosphate + H2O = D-glucose + D-glucose 6-phosphate (according to Swiss-Prot)
  • Protein family: glycosyl hydrolase 4 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: membrane associated PubMed

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References