sdpA

168

required for SdpC toxin maturation

Locus: BSU_33750

Molecular weight: 18.51 kDa

Isoelectric point: 9.77

Protein length: 158 aa

Gene length: 477 bp

Function: maturation of the SdpC toxin

Product: unknown

Essential: no

Synonyms: sdpA, yvaW

Genomic Context

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List of homologs in different organisms

Gene

Coordinates: 3,464,289  3,464,765

The protein

Structure

• O34889 (AlphaFold)

Paralogous protein(s)

• YitP

Localization

• cytoplasm PubMed

Expression and Regulation

Operons

• Genes: sdpA-sdpB-sdpC

  Description: PubMed

  Regulation

  • expressed under conditions that trigger sporulation (Spo0A) PubMed

  Expression

  • expression is heterogeneous PubMed

  Regulatory mechanism

  • Spo0A: activation, PubMed, in spo0A regulon
  • Rok: repression, PubMed, in rok regulon
  • AbrB: repression, PubMed, in abrB regulon

  Additional information

  • the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed

Biological materials

Mutant

• MGNA-A453 (yvaW::erm), available at the NBRP B. subtilis, Japan
• BKE33750 (sdpA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTACAGTAATAATTCCCT,  downstream forward: _UP4_GTATGAAGATATTAAATAGT
• BKK33750 (sdpA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTACAGTAATAATTCCCT,  downstream forward: _UP4_GTATGAAGATATTAAATAGT

References

Reviews

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Original Publications

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