artQ

168

high affinity arginine ABC transporter (permease)

Locus: BSU_23970

Molecular weight: 23.75 kDa

Isoelectric point: 9.08

Protein length: 219 aa

Gene length: 660 bp

Function: arginine uptake

Product: high affinity arginine ABC transporter (permease)

Essential: no

Synonyms: artQ, yqiY

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0765 (Galperin et al., 2021)

Gene

Coordinates: 2,491,289  2,491,948

The protein

Catalyzed reaction/ biological activity

• transport of arginine

Protein family

• Binding-protein-dependent transport system permease family (according to UniProt)

Domains

• ABC transmembrane type-1 domain (aa 19-208) (according to UniProt)

Structure

• 4YMS (PDB) (from Caldanaerobacter subterraneus, 44% identity) PubMed
• P54536 (AlphaFold)

Localization

• cell membrane PubMed

Expression and Regulation

Operons

• Genes: artP-artQ-artR

  Description: PubMed

  Regulation

  • repressed by casamino acids PubMed
  • induced in the absence of RnpM PubMed

  Regulatory mechanism

  • RnpM: unknown, PubMed, in rnpM regulon

Biological materials

Mutant

• GP1689 Δ(artP-artQ-artR)::mls, available in Jörg Stülke's lab
• GP4156 (ΔrocC::aphA3, ΔartP-artQ-artR::ermC, ΔrocE::tet,), available in Jörg Stülke's lab
• MGNA-C382 (artQ::erm), available at the NBRP B. subtilis, Japan
• BKE23970 (artQ::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAGCCTTTGTCTCCTTTT,  downstream forward: _UP4_GCTGTAGAAAGGAAGCTGAA
• BKK23970 (artQ::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAGCCTTTGTCTCCTTTT,  downstream forward: _UP4_GCTGTAGAAAGGAAGCTGAA

References

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