pksB

168

involved in polyketide synthesis

Locus: BSU_17090

Molecular weight: 25.76 kDa

Isoelectric point: 6.59

Protein length: 225 aa

Gene length: 678 bp

Function: polyketide synthesis

Product: unknown

Essential: no

Synonyms: pksB

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0491 (Galperin et al., 2021)

Gene

Coordinates: 1,782,713  1,783,390

The protein

Protein family

• metallo-beta-lactamase superfamily (according to UniProt)

Structure

• 4YSB (PDB) (from Myxococcus xanthus, 28% identity) PubMed
• O34769 (AlphaFold)

Expression and Regulation

Operons

• Genes: pksB-pksC-pksD-pksE-acpK-pksF-pksG-pksH-pksI-pksJ-pksL-pksM-pksN-pksR

  Description: PubMed

Biological materials

Mutant

• BKE17090 (pksB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTATACCATCCCTATCA,  downstream forward: _UP4_TAATCCTTCTGAATCTATTA
• BKK17090 (pksB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTATACCATCCCTATCA,  downstream forward: _UP4_TAATCCTTCTGAATCTATTA

References

Research papers

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