cdsA

168

phosphatidate cytidylyltransferase

Locus: BSU_16540

Molecular weight: 30.06 kDa

Isoelectric point: 7.87

Protein length: 269 aa

Gene length: 810 bp

Function: biosynthesis of phospholipids

Product: phosphatidate cytidylyltransferase

Essential: yes

E.C.: 2.7.7.41

Synonyms: cdsA

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0575 (Galperin et al., 2021)

Gene

Coordinates: 1,722,000  1,722,809

Phenotypes of a mutant

• essential PubMed

The protein

Catalyzed reaction/ biological activity

• 1,2-diacyl-sn-glycero-3-phosphate + CTP + H⁺ --> CDP-1,2-diacyl-sn-glycerol + diphosphate (according to UniProt)

Protein family

• CDS family (single member, according to UniProt)

Structure

• 4Q2G (PDB) (from Thermotoga maritima, 36% identity) PubMed
• O31752 (AlphaFold)

Localization

• cell membrane at the septum PubMed

Expression and Regulation

Operons

• Genes: uppS-cdsA-ispC-rasP-proS-polC

  Description: PubMed

Additional information

• the mRNA is very stable (> 15 min) PubMed

References

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