proS

168

prolyl-tRNA synthetase

Locus: BSU_16570

Molecular weight: 63.13 kDa

Isoelectric point: 5.01

Protein length: 564 aa

Gene length: 1695 bp

Function: translation

Product: prolyl-tRNA synthetase

Essential: yes

E.C.: 6.1.1.15

Synonyms: proS

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0442 (Galperin et al., 2021)

Gene

Coordinates: 1,725,330  1,727,024

Phenotypes of a mutant

• essential PubMed

The protein

Catalyzed reaction/ biological activity

• ATP + L-proline + tRNA^Pro --> AMP + diphosphate + L-prolyl-tRNA^Pro (according to UniProt)

Protein family

• Class-II aminoacyl-tRNA synthetase family (according to UniProt)

Structure

• 2I4L (PDB) (from Rhodopseudomonas palustris, 51% identity, 71% similarity) PubMed
• O31755 (AlphaFold)

Localization

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

• Genes: ispC-rasP-proS-polC

  Description: PubMed

• Genes: uppS-cdsA-ispC-rasP-proS-polC

  Description: PubMed

References

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