yddT

168

unknown

Locus: BSU_05100

Molecular weight: 25.31 kDa

Isoelectric point: 9.55

Protein length: 228 aa

Gene length: 688 bp

Function: unknown

Product: unknown

Essential: no

Synonyms: yddT

Genomic Context

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List of homologs in different organisms

Gene

Coordinates: 556,762 → 557,449

The protein

Structure

• P96657 (AlphaFold)

Paralogous protein(s)

• YomL  (the two proteins differ in only 4 out of 228 amino acids)

Expression and Regulation

Operons

• Genes: yddT

  Description: PubMed

  Regulatory mechanism

  • AbrB: repression, PubMed, in abrB regulon

Biological materials

Mutant

• MGNA-C164 (yddT::erm), available at the NBRP B. subtilis, Japan
• BP116 (yddT::spc), available inFabian Commichau's lab PubMed

Expression vectors

• IPTG inducible expression of Strep-yddT in E. coli: pGP2581 (in pGP172), available in Jörg Stülke's lab

References

Michna RH, Commichau FM, Tödter D, Zschiedrich CP, Stülke J SubtiWiki-a database for the model organism Bacillus subtilis that links pathway, interaction and expression information. Nucleic acids research. 2014 Jan; 42(Database issue):D692-8. doi:10.1093/nar/gkt1002. PMID:24178028
Commichau FM, Pietack N, Stülke J Essential genes in Bacillus subtilis: a re-evaluation after ten years. Molecular bioSystems. 2013 Jun; 9(6):1068-75. doi:10.1039/c3mb25595f. PMID:23420519
Chumsakul O, Takahashi H, Oshima T, Hishimoto T, Kanaya S, Ogasawara N, Ishikawa S Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional regulation. Nucleic acids research. 2011 Jan; 39(2):414-28. doi:10.1093/nar/gkq780. PMID:20817675
Thomaides HB, Davison EJ, Burston L, Johnson H, Brown DR, Hunt AC, Errington J, Czaplewski L Essential bacterial functions encoded by gene pairs. Journal of bacteriology. 2007 Jan; 189(2):591-602. . PMID:17114254