rnpB

168

RNA component of RNase P

Locus: BSU_misc_RNA_35

Gene length: 401 bp

Function: cleavage of precursor sequences from the 5 ends of pre-tRNAs

Product: RNA component of ribonuclease P (RNase P) (catalytic subunit, ribozyme)

Essential: yes

Synonyms: rnpB, rnaP

Genomic Context

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Gene

Phenotypes of a mutant

• essential PubMed

RNA

Catalyzed reaction/ biological activity

• processing of tRNAs

Effectors of RNA activity

• RnpM PubMed

Additional information

• K_D (RnpA-RnpB interaction): 40 nM PubMed
• K_D (RnpM-RnpB interaction): 460 pM PubMed

The protein

Structure

• 3DHS (PDB) catalytic domain of Geobacillus stearothermophilus RNase P RNA PubMed
• 3Q1R (PDB) (complex of RnpA with RnpB and trnA-Ile, from Thermotoga maritima) PubMed

Expression and Regulation

Operons

• Genes: gpsB-rnpB-ypsC

  Description: PubMed

• Genes: rnpB-ypsC

  Description: PubMed

Labs working on this gene/protein

• Carol Fierke, University of Michigan, Ann Arbor, USA homepage
• Roland Hartmann, Marburg University, Germany homepage

References

Reviews

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Original Publications

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