Difference between revisions of "RecD2"
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− | * '''Description:''' | + | * '''Description:''' 5'-3' DNA helicase replication fork progression <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || 5'-3' DNA helicase |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || replication fork progression |
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27480 RecD2] | ||
+ | |- | ||
+ | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=RecD2 RecD2] | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 88 kDa, 5.08 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 88 kDa, 5.08 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrrD]]'', ''[[yrrB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrrD]]'', ''[[yrrB]]'' | ||
|- | |- | ||
− | |style="background:#FAF8CC;" align="center"|'''[http:// | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27480 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27480 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27480 DNA_with_flanks] |
− | |||
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yrrC_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yrrC_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
+ | |- | ||
+ | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yrrC_2806286_2808682_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:yrrC_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27480]] | ||
|- | |- | ||
|} | |} | ||
__TOC__ | __TOC__ | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/><br/><br/> | ||
+ | <br/><br/> | ||
+ | |||
+ | = [[Categories]] containing this gene/protein = | ||
+ | {{SubtiWiki category|[[DNA replication]]}} | ||
+ | |||
+ | = This gene is a member of the following [[regulons]] = | ||
− | |||
=The gene= | =The gene= | ||
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=== Basic information === | === Basic information === | ||
− | * ''' | + | * '''Locus tag:''' BSU27480 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
+ | * modest increase in spontaneous mutation rate {{PubMed|24443534}} | ||
=== Database entries === | === Database entries === | ||
Line 47: | Line 61: | ||
=== Additional information=== | === Additional information=== | ||
− | |||
=The protein= | =The protein= | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
− | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
− | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
− | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
+ | ** [[SsbA]]-[[RecD2]] {{PubMed|24443534,21170359}} | ||
− | * '''Localization:''' | + | * '''[[Localization]]:''' |
=== Database entries === | === Database entries === | ||
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* '''Structure:''' | * '''Structure:''' | ||
− | * ''' | + | * '''UniProt:''' [http://www.uniprot.org/uniprot/O34481 O34481] |
− | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU27480] |
* '''E.C. number:''' | * '''E.C. number:''' | ||
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* '''Operon:''' | * '''Operon:''' | ||
− | * '''Sigma factor:''' | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yrrC_2806286_2808682_-1 recD2] {{PubMed|22383849}} |
+ | |||
+ | * '''[[Sigma factor]]:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
Line 97: | Line 113: | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Line 118: | Line 134: | ||
=References= | =References= | ||
+ | <pubmed> 21170359 24443534 </pubmed> | ||
− | + | [[Category:Protein-coding genes]] |
Latest revision as of 17:51, 22 January 2014
- Description: 5'-3' DNA helicase replication fork progression
Gene name | yrrC |
Synonyms | |
Essential | no |
Product | 5'-3' DNA helicase |
Function | replication fork progression |
Gene expression levels in SubtiExpress: RecD2 | |
Interactions involving this protein in SubtInteract: RecD2 | |
MW, pI | 88 kDa, 5.08 |
Gene length, protein length | 2394 bp, 798 aa |
Immediate neighbours | yrrD, yrrB |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27480
Phenotypes of a mutant
- modest increase in spontaneous mutation rate PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34481
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Brian W Walsh, Samantha A Bolz, Sarah R Wessel, Jeremy W Schroeder, James L Keck, Lyle A Simmons
RecD2 helicase limits replication fork stress in Bacillus subtilis.
J Bacteriol: 2014, 196(7);1359-68
[PubMed:24443534]
[WorldCat.org]
[DOI]
(I p)
Audrey Costes, François Lecointe, Stephen McGovern, Sophie Quevillon-Cheruel, Patrice Polard
The C-terminal domain of the bacterial SSB protein acts as a DNA maintenance hub at active chromosome replication forks.
PLoS Genet: 2010, 6(12);e1001238
[PubMed:21170359]
[WorldCat.org]
[DOI]
(I e)